From Michael Howard:

The Microsoft Solutions for Security (MSS) team has released The Antivirus Defense-in-Depth Guide on the Web  @
http://go.microsoft.com/fwlink/?LinkId=28734

  • A high-level overview of different malware types such as viruses and worms, their characteristics and replication techniques, and the payloads or actions malware use to attack computers.
  • How to use defense-in-depth planning for both the clients and servers in your organization, including patch management, firewall protection, general security measures, and related tools to reduce the risk of infection.
  • A comprehensive step-by-step methodology to quickly and effectively respond to malware outbreaks or infections and recover from them. The guidance in this area is based largely on Microsoft internal operations and the experience Microsoft has gained from assisting customers.